Analysis of four scales for global severity evaluation in Parkinson's disease
| Autor: | Pablo Martinez-Martin, William Fernandez, Marcos Serrano-Dueñas, Tomoko Arakaki, Kallol Ray Chaudhuri, Pedro Chana-Cuevas, Ivonne Pedroso Ibañez, Víctor Campos Arillo, Jose Manuel Rojo-Abuin, Nelida Garretto, Mario Álvarez, Carmen Rodriguez-Blazquez, Juan Carlos Martínez-Castrillo, Mayela Rodríguez-Violante, Marcelo Merello |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Parkinson's disease CIENCIAS MÉDICAS Y DE LA SALUD Concordance Ciencias de la Salud Spearman's rank correlation coefficient Article 03 medical and health sciences Cellular and Molecular Neuroscience purl.org/becyt/ford/3.3 [https] 0302 clinical medicine Quality of life Parkinsons disease Medicine global severity Depression (differential diagnoses) business.industry CISI-PD four scales medicine.disease 030227 psychiatry Otras Ciencias de la Salud Neurology Outcomes research Parkinson’s disease Clinical Global Impression Physical therapy Anxiety purl.org/becyt/ford/3 [https] Neurology (clinical) medicine.symptom business Neurological disorders 030217 neurology & neurosurgery Kappa |
| Zdroj: | Repisalud Instituto de Salud Carlos III (ISCIII) Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid Consejería de Sanidad de la Comunidad de Madrid NPJ Parkinson's Disease CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| Popis: | Global evaluations of Parkinson?s disease (PD) severity are available, but their concordance and accuracy have not been previously tested. The present international, cross-sectional study was aimed at determining the agreement level among four global scales for PD (Hoehn and Yahr, HY; Clinical Global Impression of Severity, CGIS; Clinical Impression of Severity Index, CISI-PD; and Patient Global Impression of Severity, PGIS) and identifying which of them better correlates with itemized PD assessments. Assessments included additional scales for evaluation of the movement impairment, disability, affective disorders, and quality of life. Spearman correlation coefficients, weighted and generalized kappa, and Kendall?s concordance coefficient were used. Four hundred thirty three PD patients, 66% in HY stages 2 or 3, mean disease duration 8.8 years, were analyzed. Correlation between the global scales ranged from 0.60 (HY with PGIS) to 0.91 (CGIS with CISI-PD). Kendall?s coefficient of concordance resulted 0.76 (P |
| Databáze: | OpenAIRE |
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