Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men
| Autor: | Angelo Cagnacci, Gian Benedetto Melis, Serenella Arangino, Marco Angiolucci, Anna Maria Beatrice Vacca, Annibale Volpe, Giorgio Longu |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty vascular reactivity Epinephrine melatonin BLOOD PRESSURE Blood Pressure Cardiovascular System Melatonin Norepinephrine (medication) Norepinephrine Double-Blind Method Oral administration Internal medicine medicine.artery medicine Humans business.industry Free Radical Scavengers Blood pressure Endocrinology medicine.anatomical_structure Regional Blood Flow Pulsatile Flow Catecholamine Female Internal carotid artery Cardiology and Cardiovascular Medicine business hormones hormone substitutes and hormone antagonists medicine.drug Artery |
| Zdroj: | The American journal of cardiology. 83(9) |
| ISSN: | 0002-9149 |
| Popis: | In this study it was investigated whether the oral administration of melatonin (1 mg) in comparison to placebo was able to reduce blood pressure, vascular reactivity, and catecholamines in men, as previously reported in young women. The administration of melatonin significantly reduced blood pressure, the pulsatility index in the internal carotid artery, and catecholamines levels within 90 minutes. The effect of melatonin on the artery pulsatility index was related to baseline values, being greater in men with higher baseline values. The present data indicate that melatonin may blunt the activity of the cardiovascular system and may have both physiopathologic and clinical implications. |
| Databáze: | OpenAIRE |
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