Behavioral Sensitization in Humans
Autor: | Stephen M. Strakowski, Kenji W. Sax |
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Rok vydání: | 2001 |
Předmět: |
Central Nervous System
Psychosis medicine.medical_treatment Medicine (miscellaneous) Behavioral sensitization Cocaine medicine Animals Humans Animal species Sensitization Neuronal Plasticity Blinking Amphetamines Brain General Medicine medicine.disease Stimulant Psychiatry and Mental health Clinical Psychology Stereotypy (non-human) medicine.anatomical_structure Behavioral response Animal studies Psychology Neuroscience |
Zdroj: | Journal of Addictive Diseases. 20:55-65 |
ISSN: | 1545-0848 1055-0887 |
DOI: | 10.1300/j069v20n03_06 |
Popis: | Behavioral sensitization is the process whereby repeated, intermittent stimulant administration produces a progressively greater and enduring behavioral response. For over two decades, behavioral sensitization has been reliably demonstrated in a number of different animal species and has been proposed as a model for the development of stimulant dependence. However, the application of this model to humans is limited since there have been relatively few studies of sensitization in human subjects. Nonetheless, results from these studies suggest that, similar to animal studies, enhanced behavioral responses do occur following repeated stimulant administration that resemble sensitization. Further research is necessary to examine characteristics of sensitization in humans, including the neurobiological systems involved. |
Databáze: | OpenAIRE |
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