Postinfantile giant-cell hepatitis associated with ulcerative colitis and autoimmune hepatitis
Autor: | Stavros Tsiakos, George K. Anagnostopoulos, George Margantinis, Dimitrios Arvanitidis, Kyriakos Grigoriadis, Panagiotis Kostopoulos |
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Rok vydání: | 2006 |
Předmět: |
Adult
medicine.medical_specialty Cholangiopancreatography Magnetic Resonance Biopsy Autoimmune hepatitis medicine.disease_cause Inflammatory bowel disease Gastroenterology Giant Cells Autoimmunity Diagnosis Differential Internal medicine medicine Humans Autoimmune disease Hepatology medicine.diagnostic_test business.industry medicine.disease Ulcerative colitis Hepatitis Autoimmune Liver Giant cell Liver biopsy Immunology Colitis Ulcerative Female business |
Zdroj: | Journal of gastroenterology and hepatology. 21(12) |
ISSN: | 0815-9319 |
Popis: | Postinfantile giant cell hepatitis (PGCH) is rare. It is characterized by the presence of multinucleated giant cells in liver biopsy, and although it has been associated with several etiological agents, in many cases its etiology remains unclear. The case is presented herein of an adult woman with PGCH in the setting of ulcerative colitis and autoimmune hepatitis. The presence of autoimmune hepatitis in the patient is consistent and supports the autoimmune pathogenesis of PGCH in a subgroup of patients. Furthermore, this finding, along with others, suggests that PGCH may be included in the list of hepatic complications of inflammatory bowel disease. |
Databáze: | OpenAIRE |
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