Complement-Modulating Properties of a Kaempferol 7-O-Rhamnosylsophoroside from the Leaves ofMorinda morindoides
| ISSN: | 1439-0221 0032-0943 |
|---|---|
| DOI: | 10.1055/s-2006-957657 |
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dc5521b1a540e0c21e00e9d7217ed9 https://doi.org/10.1055/s-2006-957657 |
| Rights: | CLOSED |
| Přírůstkové číslo: | edsair.doi.dedup.....a8dc5521b1a540e0c21e00e9d7217ed9 |
| Autor: | A. J. Vlietinck, P. Bakana, D. Vanden Berghe, T. De Bruyne, L. Tona, K. Kambu, B. Van Poel, Y. L. Ma, Magda Claeys, K. Cimanga, Luc Pieters |
| Rok vydání: | 1997 |
| Předmět: |
Molecular Sequence Data
Flavonoid Pharmaceutical Science Pharmacognosy Biology Analytical Chemistry chemistry.chemical_compound Drug Discovery Glycosides Kaempferols Complement Activation Flavonoids Pharmacology chemistry.chemical_classification Complement (group theory) Plants Medicinal Natural product Molecular Structure Traditional medicine Organic Chemistry Biological activity Complement system Plant Leaves Carbohydrate Sequence Complementary and alternative medicine chemistry Morinda morindoides Molecular Medicine Quercetin Medicine Traditional Kaempferol |
| Zdroj: | Planta medica: natural products and medicinal plant research |
| ISSN: | 1439-0221 0032-0943 |
| DOI: | 10.1055/s-2006-957657 |
| Popis: | A kaempferol 7-O-rhamnosylsophoroside isolated from the leaves of Morinda morindoides showed dose-dependent complement-modulating properties towards both the classical (inhibiting effect) and alternative (activating effect) pathways of the complement system. Its structure was elucidated by chemical and spectroscopic methods as kaempferol 7-O-[alpha-L-rhamnopyranosyl-(1-->6)]-[beta-D-glucopyranosyl-(1-->2)]-be ta-D-glucopyranoside, a new natural product which was named morindaoside. |
| Databáze: | OpenAIRE |
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