Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptoms

Autor:	Heini Flinck, Dominik Kerimov, Bruno Luukinen, Tapio Seiskari, Janne Aittoniemi
Rok vydání:	2022
Předmět:	Microbiology (medical) Infectious Diseases SARS-CoV-2 viruses Humans COVID-19 Original Article Biosensing Techniques rapid antigen test General Medicine Antigens Viral Sensitivity and Specificity
Zdroj:	Diagnostic Microbiology and Infectious Disease
ISSN:	0732-8893
Popis:	We evaluated a rapid antigen test against SARS-CoV-2 virus (Roche-SD Biosensor; RSDB-RAT) in children and adults with respiratory symptoms compared to those with nonrespiratory symptoms or asymptomatic. Also the performance of RSDB-RAT with respect to the duration of respiratory symptoms was assessed. A viral cross-reactivity panel was included. RSDB-RAT was reliable in detecting SARS-CoV-2 in children and adults if the respiratory symptoms had endured 1 to 7 days. If the respiratory symptoms had lasted less than 1 day, the sensitivity was significantly lower. No cross-reactivity with other respiratory viruses was observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d2a6cc6c5015d5aa5966ce683bb28e https://doi.org/10.1016/j.diagmicrobio.2021.115628 Zobrazit plný text záznamu Full Text from ScienceDirect