Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study

Autor:	Sofia Rodrigues, Paula Ambrósio, A. Borges, Patrícia Rosado Pinto, Maria José Bernardo, Raquel Condeço, D. Djokovic, Abílio Lacerda, Marta Espanhol Brito
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	medicine.medical_specialty Medicine (General) Conservative management conservative management Clinical Biochemistry Asymptomatic Adnexal mass Article Iota IOTA ADNEX Model R5-920 Doenças dos Anexos Ultrasound medicine Stage (cooking) Ovarian Neoplasms business.industry ultrasound Incidence (epidemiology) adnexal mass Neoplasias dos Ovários Cancer Conservative Management medicine.disease MAC GIN Menopause benign lesions Adnexal Diseases Benign Lesions IOTA ADNEX model Radiology Adnexal Mass medicine.symptom business
Zdroj:	Diagnostics Volume 11 Issue 11 Diagnostics, Vol 11, Iss 1992, p 1992 (2021) Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP
ISSN:	2075-4418
Popis:	This prospective multicentric study aiming to determine the incidence of complications (malignant transformation, torsion or rupture) during conservative management of adnexal masses was performed in two Portuguese tertiary referral hospitals. It included ≥18-year-old, non-pregnant patients with asymptomatic adnexal masses (associated IOTA ADNEX risk of malignancy < 10%) sonographically diagnosed between January 2016 and December 2020. Conservative patient management consisted of serial clinical and ultrasound assessment up to 60 months of follow-up, spontaneous resolution of the formation or surgical excision (median follow-up: 17.8 range 9–48 months). From the 573 masses monitored (328 premenopausal and 245 postmenopausal adnexal masses), no complications were observed in 99.5%. The annual lesion growth rates and increases in morphological complexity were similar in the premenopausal and postmenopausal patients. Spontaneous resolution, evidenced in 16.4% of the patients, was more common in the premenopausal group (p < 0.05). Surgical intervention was performed in 18.4% of the cases one borderline and one invasive FIGO IA stage cancer were diagnosed. There was an isolated case of ovary torsion (0.17%). These data support conservative management as a safe option for sonographically benign, stable and asymptomatic adnexal masses before and after menopause and highlight the need for expedite treatment of symptomatic or increased-morphological-complexity lesions.
Databáze:	OpenAIRE
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