Legionella in two splenectomized patients. Coincidence or causal relationship?
| Autor: | Irena Alon, Dorit Almoznino-Sarafian, Oleg Gorelik, Neta Cohen, I Boldur, David Modai, Z Lazarovich |
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| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Legionella longbeachae Legionella Legionella micdadei Legionella Pneumonia Legionella hackeliae medicine.disease_cause Internal medicine Streptococcus pneumoniae medicine Humans Intensive care medicine biology business.industry General Medicine bacterial infections and mycoses biology.organism_classification medicine.disease Antibodies Bacterial respiratory tract diseases Causality Community-Acquired Infections Pneumonia Infectious Diseases Splenectomy bacteria Legionnaires' disease Female Legionnaires' Disease business |
| Zdroj: | Infection. 32(3) |
| ISSN: | 0300-8126 |
| Popis: | We describe two splenectomized patients admitted with pneumonia. The course in one was complicated by overwhelming multiorgan failure when the only indicative laboratory result was seropositivity for Legionella hackeliae and Legionella longbeachae. He was initially treated with ceftriaxone and roxithromycin, followed by levofloxacin as well as intensive supportive treatment, and survived. The second patient was seroreactive for Legionella micdadei. In some cases of pneumonia in splenectomized patients tentatively considered to be caused by Streptococcus pneumoniae, the causative agent might have, in fact, been Legionella. We suggest that splenectomy be considered a possible predisposing factor for Legionella pneumonia. Since prompt diagnosis of Legionella infection, especially the non- pneumophila species, is extremely difficult, alertness to this diagnostic option and early empirical initiation of appropriate aggressive antibiotic treatment may be of critical importance. |
| Databáze: | OpenAIRE |
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