Bat coronavirus phylogeography in the Western Indian Ocean
| Autor: | Yann Gomard, Steven M. Goodman, Léa Joffrin, Camille Lebarbenchon, Eduardo Samo Gudo, Patrick Mavingui, Rajendraprasad Sookhareea, Pablo Tortosa, Erwan Lagadec, David A. Wilkinson, M. Corrie Schoeman, Andréa Dos Santos, Beza Ramasindrazana, Simon Julienne, Gildas Le Minter |
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| Přispěvatelé: | Processus Infectieux en Milieu Insulaire Tropical (PIMIT), Centre National de la Recherche Scientifique (CNRS)-IRD-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR), Association Vahatra [Antananarivo, Madagascar], Schlumberger-Doll Research, Schlumberger, European Southern Observatory (ESO), Eduardo Mondlane University, Instituto nacional de saude [Lisbon, Portugal], Tortosa, Pablo, Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IRD-Centre National de la Recherche Scientifique (CNRS), Field Museum of Natural History [Chicago, USA], Institut Pasteur de Madagascar, Réseau International des Instituts Pasteur (RIIP), University of KwaZulu-Natal [Durban, Afrique du Sud] (UKZN), National Parks and Conservation Service, Partenaires INRAE, Ministry of health of Seychelles, Instituto Nacional de Saude [Maputo, Mozambique] (INS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pollination
lcsh:Medicine Ecosystem services Chiroptera Zoonoses [SDV.EE.ECO] Life Sciences [q-bio]/Ecology environment/Ecosystems Prevalence lcsh:Science Phylogeny 0303 health sciences Multidisciplinary Phylogenetic tree [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] Alphacoronavirus Phylogeography Key (lock) Coronavirus Infections animal structures Seed dispersal Zoology Biology Real-Time Polymerase Chain Reaction Host Specificity Article Evolution Molecular 03 medical and health sciences Betacoronavirus Viral reservoirs [SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/Ecosystems Indian Ocean Islands [SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] [SDV.EE.SANT] Life Sciences [q-bio]/Ecology environment/Health Animals 14. Life underwater Viral evolution Ecosystem 030304 developmental biology [SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/Health Base Sequence 030306 microbiology Host (biology) lcsh:R Genetic Variation 15. Life on land RNA-Dependent RNA Polymerase [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology Biodiversity hotspot DNA Viral lcsh:Q [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology |
| Zdroj: | Scientific Reports Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.6873. ⟨10.1038/s41598-020-63799-7⟩ Scientific Reports, 2020, 10 (1), pp.6873. ⟨10.1038/s41598-020-63799-7⟩ Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020) |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-63799-7⟩ |
| Popis: | Bats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). The islands of the Western Indian Ocean are identified as a major biodiversity hotspot, with more than 50 bat species. In this study, we tested 1,013 bats belonging to 36 species from Mozambique, Madagascar, Mauritius, Mayotte, Reunion Island and Seychelles, based on molecular screening and partial sequencing of the RNA-dependent RNA polymerase gene. In total, 88 bats (8.7%) tested positive for coronaviruses, with higher prevalence in Mozambican bats (20.5% ± 4.9%) as compared to those sampled on islands (4.5% ± 1.5%). Phylogenetic analyses revealed a large diversity of α- and β-CoVs and a strong signal of co-evolution between CoVs and their bat host species, with limited evidence for host-switching, except for bat species sharing day roost sites.ImportanceThis is the first study to report the presence of coronaviruses (CoVs) in bats in Mayotte, Mozambique and Reunion Island, and in insectivorous bats in Madagascar. Eight percent of the tested bats were positive for CoVs, with higher prevalence in continental Africa than on islands. A high genetic diversity of α- and β-CoVs was found, with strong association between bat host and virus phylogenies, supporting a long history of co-evolution between bats and their associated CoVs in the Western Indian Ocean. These results highlight that strong variation between islands does exist and is associated with the composition of the bat species community on each island. Future studies should investigate whether CoVs detected in these bats have a potential for spillover in other hosts. |
| Databáze: | OpenAIRE |
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