Henoch-Schoenlein purpura and acute interstitial nephritis after intravenous vancomycin administration in a patient with a staphylococcal infection

Autor: Ch. Stathakis, K. Aroni, Lydia Nakopoulou, George Vaiopoulos, C Revenas, Sonia Michail, T Thosios, P Karam
Rok vydání: 1998
Předmět:
Zdroj: Scandinavian journal of rheumatology. 27(3)
ISSN: 0300-9742
Popis: We describe a case of Henoch-Schoenlein purpura, associated with oliguric acute renal failure due to acute interstitial nephritis histologically proven, in a patient with a staphylococcal chest infection. The clinical syndrome appeared twice after vancomycin administration and yielded on the withdrawal of the drug. As pathogenetic mechanism we propose an anaphylactoid reaction either to vancomycin or to a staphylococcal glycoprotein released after breakdown of the microbial cells caused by vancomycin.
Databáze: OpenAIRE