Chiral quantification of D-, L-phenylglycine mixture using mass spectrometric kinetic method
| Autor: | Liu Zhiqiang, Liu Shu-ying, Li Ming, Jin Qinhan, Chen Huanwen |
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| Rok vydání: | 2005 |
| Předmět: |
Electrospray
Spectrometry Mass Electrospray Ionization Chromatography Chemistry organic chemicals Electrospray ionization Glycine Stereoisomerism Mass spectrometry Tandem mass spectrometry Dissociation (chemistry) Kinetics polycyclic compounds Physics::Atomic and Molecular Clusters heterocyclic compounds Ion trap Enantiomer Spectroscopy |
| Zdroj: | Journal of mass spectrometry : JMS. 40(8) |
| ISSN: | 1076-5174 |
| Popis: | A novel mass spectrometric method is applied to rapid, accurate, quantitative analysis of chiral phenylglycine. Transition-metal-bound complex ions containing the chiral phenylglycine are generated by electrospray ionization mass spectrometry and subjected to collision-induced dissociation. The ratio of the two competitive dissociation rates is related to the enantiomeric composition of the mixture, allowing the determination of enantiomeric contamination in the intermediates. |
| Databáze: | OpenAIRE |
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