Does Alzheimer's Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes?
| Autor: | Guoquan Xu, Tamara G. Fong, Yun R. Gou, Richard N. Jones, Tammy T. Hshieh, Edward R. Marcantonio, Eva M. Schmitt, Thomas G. Travison, Eran D. Metzger, Sharon K. Inouye |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Activities of daily living Disease Severity of Illness Index Article 03 medical and health sciences 0302 clinical medicine Alzheimer Disease Internal medicine Outcome Assessment Health Care medicine Humans Dementia Prospective Studies 030212 general & internal medicine Prospective cohort study Aged Aged 80 and over business.industry Incidence (epidemiology) Delirium Length of Stay Mental Status and Dementia Tests medicine.disease Confidence interval Hospitalization Relative risk Female Geriatrics and Gerontology medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | J Am Geriatr Soc |
| ISSN: | 1532-5415 0002-8614 1722-1730 |
| DOI: | 10.1111/jgs.16420 |
| Popis: | OBJECTIVES We examined the association between delirium severity and outcomes of delirium among persons with and without Alzheimer's disease and related dementias (ADRD). DESIGN Prospective cohort study. SETTING Academic tertiary medical center. PARTICIPANTS A total of 352 medical and surgical patients. MEASUREMENTS Delirium incidence and severity were rated daily using the Confusion Assessment Method (CAM) and CAM-Severity (CAM-S) score during hospitalization. Severe delirium was defined as a CAM-S Short Form score in the highest tertile (3-7 points out of 7). ADRD status was determined by a clinical consensus process. Clinical outcomes included prolonged length of stay (>6 d), discharge to post-acute nursing facility, any decline in activities of daily living (ADLs) at 1 month from prehospital baseline, ongoing nursing facility stay, and mortality. RESULTS Patients with ADRD (n = 85 [24%]) had a significantly higher relative risk (RR) for incident delirium (RR = 2.31; 95% confidence interval [CI] = 1.64-3.28) and higher peak CAM-S scores (mean difference = 1.24 points; CI = .83-1.65; P |
| Databáze: | OpenAIRE |
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