Evaluation of CT perfusion parameters for assessment of split renal function in healthy donors
| Autor: | Ghada M. Gaballa, Mohamed A Borg, Mohamed Tarek El-Diasty, Tarek El-Diasty, Hossam M. Gad, Khaled Zaki Sheir, Mohamed E. Abou-El-Ghar |
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| Rok vydání: | 2016 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty lcsh:R895-920 Renal cortex Renal function Perfusion scanning Blood volume 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Cortex (anatomy) medicine Radiology Nuclear Medicine and imaging Quantitative analysis Perfusion parameters Kidney business.industry Intensity (physics) Renal transplant medicine.anatomical_structure Radiology Nuclear Medicine and imaging 030220 oncology & carcinogenesis CT perfusion Radiology business Perfusion |
| Zdroj: | The Egyptian Journal of Radiology and Nuclear Medicine, Vol 47, Iss 4, Pp 1681-1688 (2016) |
| ISSN: | 0378-603X |
| Popis: | Objectives To assess feasibility of automatically calculated CT perfusion parameters using two different methods of drawing regions of interest (ROIs) to reflect split renal function in comparison with MAG3 renography. Methods and materials 51 potential kidney donors (24 males, 27 females) were prospectively evaluated by preoperative CT perfusion. Post processing was done twice; one with ROI around renal cortex only and the other around cortex and medulla. Perfusion parameters (perfusion, peak enhancement intensity PEI and blood volume BV) were compared between the two methods. Split values for each of these parameters were calculated and compared to split renal function measured by MAG3 renography using paired samples t test. Results Perfusion was significantly lower in method 2 than in method 1 while PEI and BV showed no significant difference between the two methods. Split values of CT parameters showed no significant difference from corresponding renography split function (p value > 0.1) except BV by method 1 and perfusion by method 2 which showed significant difference ( p value Conclusion Certain CT perfusion parameters can reflect split renal function. Perfusion was more accurate in reflecting split renal function with ROI around the cortex while BV was more accurate with ROI around the whole parenchyma. |
| Databáze: | OpenAIRE |
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