Imedeen® for the Treatment of Degenerated Skin in Females
| Autor: | H.-P. Happonen, J. Santalahti, L. Jeskanen, Allan Lassus |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Administration Oral Placebo treatment Physiology Pilot Projects 030204 cardiovascular system & hematology Placebo Skin Diseases Biochemistry Skin thickness law.invention Nail Diseases 03 medical and health sciences 0302 clinical medicine Double-Blind Method Randomized controlled trial law Oral administration medicine Humans skin and connective tissue diseases Glycosaminoglycans Skin Chemotherapy integumentary system business.industry Biochemistry (medical) Proteins Marine fish Cell Biology General Medicine Middle Aged Elastic Tissue Response to treatment Skin Aging Surgery 030220 oncology & carcinogenesis Sunlight Female Hair Diseases business |
| Zdroj: | Journal of International Medical Research. 19:147-152 |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/030006059101900208 |
| Popis: | Imedeen®, a new compound for oral administration consisting of special protein fractions and some glucosaminoglycans extracted from marine fish, has been shown in previous pilot studies to have a repairing effect on sun-damaged skin. In an open study, 10 females with sun-damaged skin, aged 39 – 61 years, were treated with 0.5 g/day Imedeen® for 90 days. At baseline and after 30, 60 and 90 days, the following parameters were clinically evaluated: wrinkles; mottles; dryness of skin; and brittleness of hair and nails. After 90 days' treatment all signs of sun-damage had improved and brittleness of hair and nails was normalized in all cases. These clinical observations were confirmed by changes in skin thickness and elasticity. In a second double-blind study, 30 females in the same age range and with similar signs of sun-damage were treated with 0.5 g/day Imedeen® or placebo for 90 days. The results in the Imedeen®-treated group corresponded to those in the first study whereas no response to treatment was observed in the placebo treatment group. |
| Databáze: | OpenAIRE |
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