Identification of a novel lineage of Crimean–Congo haemorrhagic fever virus in dromedary camels, United Arab Emirates
| Autor: | Saeed M Alyammahi, Anna Uehara, Yan Li, Esmat F Gasim, Ibrahim H Ibrahim, M. F. M. Yusof, Eric Bergeron, Jing Zhang, Hassan Z. A. Ishag, Abdelmalik I. Khalafalla, Mohamed A Al Hosani, Zulaikha M Alhammadi, Nasareldien A Hussein, Salama S Almuhairi, Farida A L Hosani, Ying Tao, Suxiang Tong, Susan I. Gerber |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
endocrine system Lineage (genetic) Camelus Animal Reverse Transcriptase Polymerase Chain Reaction 030231 tropical medicine Reassortment Crimean-Congo haemorrhagic fever virus United Arab Emirates Genome Viral Biology Virology Genome Virus Serology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Vector (epidemiology) Case fatality rate Hemorrhagic Fever Virus Crimean-Congo Animals Hemorrhagic Fever Crimean |
| Zdroj: | J Gen Virol |
| Popis: | Crimean–Congo haemorrhagic fever virus (CCHFV) is a tick-borne virus causing Crimean–Congo haemorrhagic fever (CCHF), a disease reported to have a high fatality rate in numerous countries. The virus is geographically widespread due to its vector, and numerous wild and domestic animals can develop asymptomatic infection. Serological and limited molecular evidence of CCHFV has previously been reported in Camelus dromedarius (the dromedary, or one-humped camel) in the United Arab Emirates (UAE). In this study, 238 camel samples were screened for CCHFV RNA where 16 camel samples were positive for CCHFV by RT-PCR. Analysis of full-length CCHFV genome sequences revealed a novel lineage in camels from the UAE, and potential reassortment of the M segment of the genome. |
| Databáze: | OpenAIRE |
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