Association between short and long sleep durations and cardiovascular outcomes: a systematic review and meta-analysis

Autor: Mehmet Aydar, Chayakrit Krittanawong, Zhen Wang, Anusith Tunhasiriwet, Takeshi Kitai, Sakkarin Chirapongsathorn, Larry J. Prokop, Tao Sun, Hongju Zhang
Rok vydání: 2017
Předmět:
0301 basic medicine
medicine.medical_specialty
Time Factors
Coronary Disease
Disease
Type 2 diabetes
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Sensitivity and Specificity
03 medical and health sciences
0302 clinical medicine
Asian People
Risk Factors
Internal medicine
Medicine
Humans
030212 general & internal medicine
Duration (project management)
Risk factor
Aged
Randomized Controlled Trials as Topic
Metabolic Syndrome
Short sleep
business.industry
Leptin
digestive
oral
and skin physiology
Hazard ratio
General Medicine
Odds ratio
medicine.disease
Stroke
Observational Studies as Topic
030104 developmental biology
Diabetes Mellitus
Type 2
Cardiovascular Diseases
Meta-analysis
Long sleep
Ghrelin
Observational study
Female
Metabolic syndrome
Cardiology and Cardiovascular Medicine
business
Sleep
Cardiovascular outcomes
hormones
hormone substitutes
and hormone antagonists
030217 neurology & neurosurgery
Zdroj: European heart journal. Acute cardiovascular care. 8(8)
ISSN: 2048-8734
Popis: Background: A shorter sleep duration has been identified as a risk factor for cardiovascular diseases and increased mortality. It has been hypothesized that a short sleep duration may be linked to changes in ghrelin and leptin production, leading to an alteration of stress hormone production. Here, we conducted a systematic review and meta-analysis to investigate the potential relationship between a sleep duration and cardiovascular disease mortality. Methods: We conducted a comprehensive search of Ovid Medline In-Process and other non-indexed citations, Ovid MEDLINE, Ovid Embase, Ovid Cochrane Central Register of Controlled Trials, and Scopus from database inception to March 2017. Observational studies were included if the studies reported hazard ratios or odds ratios of the associations between sleep durations (short and long) and cardiovascular disease mortality. Data were extracted by a reviewer and then reviewed by two separate reviewers. Conflicts were resolved through consensus. Using the DerSimonian and Laird random effects models, we calculated pooled hazard ratios and pooled odds ratios with 95% confidence intervals (CI). Subgroup analyses were performed to explore potential sources of heterogeneity. The quality of the included studies and publication bias were assessed. Results: In total, our meta-analysis included 19 studies (31 cohorts) with a total of 816,995 individuals with 42,870 cardiovascular disease mortality cases. In pooled analyses, both short (risk ratio 1.19; 95% CI 1.13 to 1.26, P2=30.7, Pheterogeneity=0.034), and long (risk ratio 1.37; 95% CI 1.23 to 1.52, P2=79.75, PheterogeneityConclusions: Both short (9 hours) can increase the risk of overall cardiovascular disease mortality, particularly in Asian populations and elderly individuals. Future epidemiological studies would ideally include objective sleep measurements, rather than self-report measures, and all potential confounders, such as genetic variants.
Databáze: OpenAIRE
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