Subthreshold autism spectrum in bipolar disorder: Prevalence and clinical correlates
| Autor: | Filippo Maria Barberi, Camilla Gesi, Liliana Dell'Osso, Carlo Antonio Bertelloni, Elisa Diadema, Claudia Carmassi, Barbara Carpita |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Bipolar Disorder Autism Spectrum Disorder Population Comorbidity Suicidality Autistic traits 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Prevalence Humans Clinical significance Mood disorders Subthreshold symptoms Bipolar disorder education Biological Psychiatry education.field_of_study business.industry Middle Aged medicine.disease 030227 psychiatry Psychiatry and Mental health Affect Anxiety Autism Female medicine.symptom business 030217 neurology & neurosurgery Clinical psychology |
| Popis: | Background While few previous studies highlighted a higher prevalence of autistic traits among adults with Bipolar Disorder (BD), little is known about their clinical significance in this population. Method 143 subjects with BD were enrolled at the adult psychiatric inpatient clinic of the University of Pisa. Assessments included the SCID-5, the MOODS-SR, the AQ and the AdAS Spectrum. Results 42.7% of the sample scored positively for significant levels of autistic traits. Subjects with high autistic traits showed a greater likelihood of a very early onset of BD, greater length of current in-hospital stay, significantly higher rates of anxiety disorders and lower rates of substance use disorders compared to patients with low autistic traits. They also show significantly greater depressive symptoms and suicidality across the lifetime. Suicidality was associated with the altered responsiveness to sensory input and inversely related to adherence to routine and inflexibility. Conclusion The study is a first exploration of the clinical significance of autistic traits among BD patients. Our results highlight the clinical significance of autistic traits in patients with BD, supporting the usefulness of a dimensional approach to the autism spectrum. |
| Databáze: | OpenAIRE |
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