Image-guided percutaneous sclerotherapy of venous malformations of the head and neck: Clinical and MR-based volumetric mid-term outcome

Autor: Markus A Möhlenbruch, Philipp Gebhart, Astrid Burger, Dominik F Vollherbst, Martin Bendszus, Steffen Kargus, Reinald Kühle, Jürgen Hoffmann, Patrick Günther
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Percutaneous
Databases
Factual
Vascular Malformations
medicine.medical_treatment
Magnetic resonance angiography
Diagnostic Radiology
Medicine and Health Sciences
Retrospective analysis
Sclerotherapy
Medicine
Head and neck
Materials
Paediatric patients
Multidisciplinary
medicine.diagnostic_test
Organic Compounds
Radiology and Imaging
Foams
Magnetic Resonance Imaging
Chemistry
Research Design
Physical Sciences
Female
Radiology
Anatomy
Research Article
Adult
medicine.medical_specialty
Imaging Techniques
Clinical Research Design
Science
Materials Science
Pain
Research and Analysis Methods
Signs and Symptoms
Diagnostic Medicine
Humans
Volume reduction
Retrospective Studies
Ethanol
business.industry
Organic Chemistry
Chemical Compounds
Biology and Life Sciences
Retrospective cohort study
Alcohols
Lesions
Adverse Events
Clinical Medicine
business
Head
Neck
Magnetic Resonance Angiography
Follow-Up Studies
Zdroj: PLoS ONE, Vol 15, Iss 10, p e0241347 (2020)
PLoS ONE
ISSN: 1932-6203
Popis: ObjectiveTo report the clinical and MRI-based volumetric mid-term outcome after image guided percutaneous sclerotherapy (PS) of venous malformations (VM) of the head and neck.MethodsA retrospective analysis of a prospectively maintained database was performed, including patients with VM of the head and neck who were treated with PS. Only patients with available pre- and post-interventional MRI were included into this study. Clinical outcome, which was subjectively assessed by the patients, their parents (for paediatric patients) and/or the physicians, was categorized as worse, unchanged, minor or major improvement. Radiological outcome, determined by MRI-based volumetric measurements, was categorized as worse (>10% increase), unchanged (≤10% increase to ResultsTwenty-seven patients were treated in 51 treatment sessions. After a mean follow-up of 31 months, clinical outcome was worse for 7.4%, unchanged for 3.7% of the patients, while there was minor and major improvement for 7.4% and 81.5%, respectively. In the volumetric imaging analysis 7.4% of the VMs were worse and 14.8% were unchanged. Minor improvement was observed in 22.2%, intermediate improvement in 44.4% and major improvement in 11.1%. The rate of permanent complications was 3.7%.ConclusionPS can be an effective therapy to treat the symptoms of patients with VMs of the head and neck and to downsize the VMs. MRI-based volumetry can be used to objectively follow the change in size of the VMs after PS. Relief of symptoms frequently does not require substantial volume reduction.
Databáze: OpenAIRE
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