MRI based 3D finite element modelling to investigate deep tissue injury
| Autor: | Kevin M. Moerman, Jules L. Nelissen, Dan L. Bader, Cees W. J. Oomens, Gustav J. Strijkers, Mark C. van Turnhout, Willeke A. Traa, Aart J. Nederveen |
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| Přispěvatelé: | Soft Tissue Biomech. & Tissue Eng., Radiology and Nuclear Medicine, ACS - Diabetes & metabolism, AMS - Restoration & Development, Amsterdam Neuroscience - Brain Imaging, ACS - Atherosclerosis & ischemic syndromes, Biomedical Engineering and Physics, AMS - Sports & Work, ACS - Heart failure & arrhythmias |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Materials science
magnetic resonance imaging (MRI) Muscle Skeletal/diagnostic imaging 0206 medical engineering Finite Element Analysis Biomedical Engineering Bioengineering 02 engineering and technology Stress SDG 3 – Goede gezondheid en welzijn Models Biological Rats sprague dawley Rats Sprague-Dawley 03 medical and health sciences 0302 clinical medicine Tibialis anterior muscle SDG 3 - Good Health and Well-being Deep tissue Models Indentation Skeletal/diagnostic imaging Animals Muscle Skeletal deep tissue injury pressure ulcer Orientation (computer vision) Animal General Medicine Mechanical Biological 020601 biomedical engineering Magnetic Resonance Imaging Finite element method Computer Science Applications 2d analysis Rats Human-Computer Interaction body regions Disease Models Animal finite element modelling (FE) Strain distribution Disease Models Muscle Sprague-Dawley Stress Mechanical indentation test 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | Computer Methods in Biomechanics and Biomedical Engineering, 21(14), 760-769. Informa Healthcare Computer methods in biomechanics and biomedical engineering, 21(14), 760-769. Informa Healthcare |
| ISSN: | 1025-5842 |
| Popis: | Pressure ulcers occur due to sustained mechanical loading. Deep tissue injury is a severe type of pressure ulcer, which is believed to originate in subcutaneous tissues adjacent to bony prominences. In previous experimental-numerical studies the relationship between internal tissue state and damage development was investigated using a 2D analysis. However, recent studies suggest that a local analysis is not sufficient. In the present study we developed a method to create animal-specific 3D finite element models of an indentation test on the tibialis anterior muscle of rats based on MRI data. A detailed description on how the animal specific models are created is given. Furthermore, two indenter geometries are compared and the influence of errors in determining the indenter orientation on the resulting internal strain distribution in a defined volume of tissue was investigated. We conclude that with a spherically-shaped indenter errors in estimating the indenter orientation do not unduly influence the results of the simulation. |
| Databáze: | OpenAIRE |
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