The Potentials and Role of Diffusion-Weighted Magnetic Resonance Imaging in Evaluating the Efficiency of Antitumor Treatment of Patients with Breast Liver Metastasis
| Autor: | А. B. Lukiyanchenko, B. М. Medvedeva, E. S. Kolobanova, К. A. Romanova, S. S. Magamedova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_treatment
R895-920 Mri studies Small liver 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences Medical physics. Medical radiology. Nuclear medicine 0302 clinical medicine Breast cancer breast cancer medicine magnetic resonance imaging In patient metastases Chemotherapy medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine medicine.disease Diffusion-Weighted Magnetic Resonance Imaging 030220 oncology & carcinogenesis diffusion-weighted magnetic resonance imaging business Nuclear medicine |
| Zdroj: | Вестник рентгенологии и радиологии, Vol 100, Iss 5, Pp 286-292 (2019) |
| ISSN: | 2619-0478 0042-4676 |
| Popis: | Objective. To compare the informative value of using dynamic magnetic resonance imaging (MRI) and diffusion-weighted MRI (DW-MRI) in patients with breast liver metastasis during chemotherapy.Material and methods. The investigation enrolled 30 patients with breast liver metastasis during their treatment. The results of standard intravenous contrast-enhanced abdominal MRI studies (by evaluating the liver in the arterial, venous, and delayed phases) were compared with those of DW-MRI with different B-factor values (50, 400 and 800 sec/mm2).Results. Comparison of the findings of initial studies prior to chemotherapy (those of only dynamic intravenous contrast-enhanced MRI and only DW-MRI) revealed a complete correspondence with the number of detected foci in 10 patients. Ten patients had a larger number of metastatic foci at DW-MRI than at intravenous contrast-enhanced MRI, in the aggregate by 44 foci more (of them 36 foci measured less than 1 cm). The remaining 10 of the 30 patients were found to have multiple, unquantifiable (more than 20–40) metastatic foci of various sizes (1–6 cm) at both intravenous contrast-enhanced MRI and DW-MRI. Nineteen of the 30 patients were followed up during their chemotherapy. Seven of the 19 patients showed a stabilized liver metastatic process that was similarly evidenced by both techniques. Eleven of the 19 patients were observed to have a progressive metastatic process that was reflected by the similar increase in the number and size of metastases in 5 of the 11 patients, as shown by both of the above techniques. In the remaining 6 of the 11 patients, the number of newly detected liver tumors proved to be larger at DW-MRI than at intravenous contrast-enhanced MRI. Both techniques showed that the last patient of the 19 cases had a decrease in the number of small liver metastases that maintained their sizes (less than 1 cm).Conclusion. DW-MRI has been shown to be much more effective in detecting metastases than conventional intravenous contrast-enhanced MRI, which necessitates the inclusion of this technique in standard abdominal MRI protocols for patients with liver metastasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|