Lactate levels with glioblastoma multiforme
Autor: | Arundeep Kahlon, Mariam Alexander, Jonathan Wright, Arunpreet Kahlon |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
medicine.diagnostic_test business.industry Deep vein Anion gap General Medicine medicine.disease Bioinformatics Thrombosis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Text mining Immune system medicine.anatomical_structure Case Studies 030220 oncology & carcinogenesis Lactic acidosis Magnetic resonance imaging of the brain medicine Cancer research business Glioblastoma |
Popis: | A 37-year-old woman with known glioblastoma multiforme was admitted for treatment of new deep vein thrombosis. Anion gap and plasma lactate levels were found to be elevated. Magnetic resonance imaging of the brain showed a stable, advanced glioblastoma multiforme. All causes of lactic acidosis, including infections and medications, were ruled out. Aggressive tumors have been shown to produce lactate levels in minute quantities in their microenvironment, which helps them metastasize and evade immune response and even radiation. |
Databáze: | OpenAIRE |
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