Immune system transcriptome in gingival tissues of young nonhuman primates
| Autor: | M. J. Novak, Sreenatha Kirakodu, Radhakrishnan Nagarajan, J. L. Ebersole, Luis Orraca, Octavio A. Gonzalez, Janis Gonzalez-Martinez |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Gingiva Inflammation Article Transcriptome 03 medical and health sciences 0302 clinical medicine Immune system medicine Animals Periodontitis Gene Oligonucleotide Array Sequence Analysis biology RNA 030206 dentistry medicine.disease biology.organism_classification Macaca mulatta Rhesus macaque 030104 developmental biology Immune System Immunology Gene chip analysis Periodontics medicine.symptom |
| Zdroj: | Journal of Periodontal Research. 51:152-163 |
| ISSN: | 0022-3484 |
| DOI: | 10.1111/jre.12293 |
| Popis: | Background and Objective Young/adolescent humans harbor many microorganisms associated with periodontal disease in adults and show substantial gingival inflammatory responses. However, younger individuals do not demonstrate the soft- and hard-tissue destruction that hallmark periodontitis. Material and Methods This study evaluated responses to the oral microbial ecology in gingival tissues from clinically healthy young Macaca mulatta ( |
| Databáze: | OpenAIRE |
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