Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

Autor:	David C. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, Jesse Miller, Kanupriya Whig, Brinda Kamalia, Mark Dittmar, Stuart Weston, Holly L. Hammond, Carly Dillen, Jeremy Ardanuy, Louis Taylor, Jae Seung Lee, Minghua Li, Emily Lee, Clarissa Shoffler, Christopher Petucci, Samuel Constant, Marc Ferrer, Christoph A. Thaiss, Matthew B. Frieman, Sara Cherry
Rok vydání:	2022
Předmět:	Alanine Multidisciplinary SARS-CoV-2 Drug Evaluation Preclinical COVID-19 Nucleosides Cytidine Hydroxylamines Antiviral Agents Adenosine Monophosphate Cell Line COVID-19 Drug Treatment Pyrimidines Humans
Zdroj:	Nature. 604:134-140
ISSN:	1476-4687 0028-0836
DOI:	10.1038/s41586-022-04482-x
Popis:	The SARS-CoV-2 virus has infected more than 261 million people and has led to more than 5 million deaths in the past year and a half
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8872425cf9f96f1ddff9e7134cc9c07 https://doi.org/10.1038/s41586-022-04482-x Zobrazit plný text záznamu Full text from SpringerLink