| Autor: |
Okafor, Roseanne Adah, Konne, Felix Eedee, Nyenke, Clement Ugochukwu, Okolonkwo, Benjamin Nnamdi, Chukwubike Udoka Okeke |
| Rok vydání: |
2022 |
| Předmět: |
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| DOI: |
10.5281/zenodo.7032979 |
| Popis: |
Malaria is one parasite that is responsible for fever in tropical countries. The genus plasmodium is an obligate intra-erythrocyticprotozoa which causes malaria. Malarial involvement with liver is now a known case with its specific biochemical aberrations. The aim of this study was to determine the effects of density of Plasmodium falciparum parasitaemia on serum liver enzymes. It was a cross sectional study of One thousand (1000) children comprising of Six hundred and ninety four (694) children with malaria taken as the test group while 306 children that had no malaria were regarded as the control group. Blood samples were collected from them and examined for malaria and Liver enzymes such as ALT, ALP and GGT. The data obtained from the study were analyzed using GraphPad Prism Version 8.0.2.263. Result gotten from the study showed that the levels of the liver enzymes reduces as the parasite density increases from moderate to high. Post hoc analysis also showed a significant difference in the levels of ALT and ALP but no significant difference in the level of GGT. This study has demonstrated that higher density of plasmodium could bring about reduction in the levels of liver enzymes. It is therefore recommended that liver function test be carried out in chronic malaria infestation to aid effective treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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