Biotransformation of osthole by Alternaria longipes

Autor:	Xiance Sun, Dan Liu, Pei Pei Dong, Zhi-Ming Wu, Rong-Gang Xi, Xiu-Lan Xin, Gang Wang, Rong Lan, Xiaobo Wang
Rok vydání:	2013
Předmět:	Pharmacology Molecular Structure Chemistry Stereochemistry Organic Chemistry Alternaria longipes Pharmaceutical Science Alternaria General Medicine Coumarin Analytical Chemistry chemistry.chemical_compound Complementary and alternative medicine Biotransformation Coumarins Drug Discovery Molecular Medicine Spectral data Nuclear Magnetic Resonance Biomolecular
Zdroj:	Journal of Asian natural products research. 15(7)
ISSN:	1477-2213
Popis:	The biotransformation of osthole (1) by Alternaria longipes was carried out, and five transformed products were obtained in the present research work. Based on their extensive spectral data, the structures of these metabolites were characterized as 4'-hydroxyl-osthole (2), 4'-hydroxyl-2',3'-dihydroosthole (3), 2',3'-dihydroxylosthole (4), osthole-4'-oic acid methyl ester (5), and osthole-4'-oic acid glucuron-1-yl ester (6), respectively. Among them, products 5 and 6 were new compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87b155917c245df5ceecab7f33f7831 https://pubmed.ncbi.nlm.nih.gov/23679093 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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