New Treatment Option for Autoimmune Enteropathy: A Rare Case of Intractable Diarrhea Treated with Vedolizumab
| Autor: | Heba Iskandar, Gordon Robbins, Jessica Tracht, Drew Davis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Abdominal pain business.industry Intractable diarrhea Treatment options Case Report General Medicine Disease Autoimmune enteropathy medicine.disease Gastroenterology Vedolizumab Small Bowel 03 medical and health sciences 0302 clinical medicine Autoimmune Process 030220 oncology & carcinogenesis Internal medicine Rare case medicine 030211 gastroenterology & hepatology medicine.symptom business medicine.drug |
| Zdroj: | ACG Case Reports Journal |
| ISSN: | 2326-3253 |
| Popis: | Autoimmune enteropathy is an uncommon cause of chronic diarrhea rarely seen in adults. The disease is secondary to an autoimmune process in the gut that leads to villous blunting and subsequent watery diarrhea, abdominal pain, and severe weight loss. The disease has only been described in 37 adults prior to our case, and variable treatment success has been documented with steroids, immunomodulators, and TNF-α inhibitors. This case is the first to show success in treating autoimmune enteropathy with vedolizumab and provides physicians with an additional therapeutic option when limited by a patient's comorbidities and side effects of other drugs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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