Serum Glycated Albumin to Guide the Diagnosis of Diabetes Mellitus

Autor:	Cyue-Huei Hua, Ying-Jhu Liao, Tse-Ya Yu, Jung-Nan Wei, Lee-Ming Chuang, Wan-Chen Wu, Hung-Yuan Li, Shyang-Rong Shih, Wen-Ya Ma, Mao-Shin Lin
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Adult Blood Glucose Glycation End Products Advanced Male medicine.medical_specialty endocrine system diseases Serum albumin lcsh:Medicine 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Sensitivity and Specificity Gastroenterology Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Diabetes mellitus Internal medicine Blood plasma Diabetes Mellitus medicine Humans Glycated Serum Albumin lcsh:Science Serum Albumin Aged Glycemic Glycated Hemoglobin Glucose tolerance test Multidisciplinary biology medicine.diagnostic_test business.industry lcsh:R nutritional and metabolic diseases Glucose Tolerance Test Middle Aged medicine.disease Endocrinology biology.protein Population study Female lcsh:Q Hemoglobin business Body mass index Biomarkers Research Article
Zdroj:	PLoS ONE, Vol 11, Iss 1, p e0146780 (2016) PLoS ONE
ISSN:	1932-6203
Popis:	In the diagnosis of diabetes mellitus, hemoglobin A1c (HbA1c) is sometimes measured to determine the need of an oral glucose tolerance test (OGTT). However, HbA1c does not accurately reflect glycemic status in certain conditions. This study was performed to test the possibility that measurement of serum glycated albumin (GA) better assesses the need for OGTT. From 2006 to 2012, 1559 subjects not known to have diabetes or to use anti-diabetic medications were enrolled. Serum GA was measured, and a 75-g OGTT was then performed to diagnose diabetes. Serum GA correlated significantly to age (r = 0.27, p
Databáze:	OpenAIRE
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