New ternary Fe(III)-8-hydroxyquinoline-reduced Schiff base complexes as selective anticancer drug candidates

Autor:	Valeria Ferretti, Cristina P. Matos, Catarina Canelas, João Costa Pessoa, Ana Isabel Tomaz, Radosław Starosta, Isabel Correia, Ignacio E. León
Rok vydání:	2022
Předmět:	Tryptophan Antineoplastic Agents Serum Albumin Bovine Ligands Oxyquinoline Biochemistry Ferric Compounds Inorganic Chemistry Molecular Docking Simulation Mice Coordination Complexes Animals Humans Cisplatin Schiff Bases Platinum
Zdroj:	Journal of inorganic biochemistry. 236
ISSN:	1873-3344
Popis:	Due to the growing prevalence of cancer diseases, new therapeutic options are urgently needed, and drugs based on metal ions other than platinum are alternatives with exciting possibilities. We report the synthesis, characterization and biological effect of mixed-ligand Fe(III)-aminophenolate complexes derived from salicylaldehyde and L-tryptophan with quinoline derivatives as co-ligands, namely 8-hydroxyquinoline (8HQ), [Fe(L)(8HQ)(H
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a871f4ee400ee73c729d96be38e32d82 https://pubmed.ncbi.nlm.nih.gov/36049258 Zobrazit plný text záznamu Full Text from ScienceDirect