Primary embryonal rhabdomyosarcoma of long bone. Case report and review of the literature
| Autor: | James R. Ryan, Yaddanapudi Ravindranath, Mark M. Zalupski, Brian Ortman, David R. Lucas, Martin L. Gross |
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| Rok vydání: | 1996 |
| Předmět: |
musculoskeletal diseases
Pathology medicine.medical_specialty Long bone Bone Neoplasms Pathology and Forensic Medicine Desmin Immunoenzyme Techniques medicine Neoplasm Humans Rhabdomyosarcoma Embryonal Femur Rhabdomyosarcoma Child neoplasms business.industry Myoglobin DNA Neoplasm medicine.disease Flow Cytometry Magnetic Resonance Imaging Actins Radiography medicine.anatomical_structure Immunohistochemistry Osteosarcoma Surgery Female Embryonal rhabdomyosarcoma Sarcoma Anatomy Differential diagnosis business |
| Zdroj: | The American journal of surgical pathology. 20(2) |
| ISSN: | 0147-5185 |
| Popis: | We report a case of primary embryonal rhabdomyosarcoma of long bone, presenting as a lytic destructive bone tumor in the right femoral diaphysis of a 7-year-old girl. To our knowledge, this is only the third report of this entity. The neoplasm was a pure embryonal rhabdomyosarcoma with numerous rhabdomyoblasts. Immunohistochemistry confirmed the diagnosis: The cells were reactive with antibodies directed against desmin, muscle-specific actin, and myoglobin. No other neoplastic mesenchymal component was present within the tumor. Although rare, primary rhabdomyosarcoma, along with Ewing's tumor and osteosarcoma, should be considered in the differential diagnosis of malignant bone tumors in childhood. |
| Databáze: | OpenAIRE |
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