N omenclature of homodetic cyclic peptides produced from ribosomal precursors: A n IUPAC task group interim report
| Autor: | Ulf Göransson, Pramodkumar D. Jadhav, Jianheng Shen, Ning-Hua Tan, Gerard P. Moss, Youn Young Shim, Martin J. T. Reaney, David J. Craik |
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| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Task group Information retrieval 010405 organic chemistry Organic Chemistry Chemical nomenclature Biophysics General Medicine Peptides Cyclic 01 natural sciences Biochemistry Cyclic peptide 0104 chemical sciences Biomaterials 010404 medicinal & biomolecular chemistry Cell and molecular biology chemistry Protein Biosynthesis Terminology as Topic Animals Humans Ribosomes Nomenclature Interim report |
| Zdroj: | Peptide Science. 106:917-924 |
| ISSN: | 1097-0282 0006-3525 |
| Popis: | In 2015, an International Union of Pure and Applied Chemistry (IUPAC) Task Group was formed to develop nomenclature recommendations for homodetic cyclic peptides produced from ribosomal precursors. Delegates of the 2015 International Conference on Circular Proteins (ICCP) were presented with the strengths and weaknesses of four published approaches to homodetic cyclic peptide nomenclature, and a summary of the ensuing discussion is presented here. This interim report presents a potentially novel suggestion – the use of Cahn-Ingold-Prelog rules to specify amino acid priority in homodetic peptides for consistent numbering. Indeed, this might be the first extension of the Cahn-Ingold-Prelog rules in five decades. The authors invite interested parties to contact the corresponding author with suggestions for the improvement of the proposed nomenclature; these ideas will be discussed and considered for inclusion in the final report. |
| Databáze: | OpenAIRE |
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