Costs of streamlined HIV care delivery in rural Ugandan and Kenyan clinics in the SEARCH Studys

Autor: Betty Mwebaza, Thomas Osmand, Asiphas Owaraganise, Dalsone Kwarisiima, Elly Assurah, Ronald Aine, Moses R. Kamya, Craig R. Cohen, Diane V. Havlir, Douglas Black, Daniel Mwai, Harsha Thirumurthy, Elizabeth A. Bukusi, Starley B. Shade, Lillian B. Brown, Vivek Jain, Maya L. Petersen, James Ayieko, Laura B. Balzer, Tamara D. Clark, Florence Mwangwa, Edwin D. Charlebois, Alex Luo
Rok vydání: 2018
Předmět:
0301 basic medicine
Rural Population
Kenya
medicine.medical_specialty
Immunology
Human immunodeficiency virus (HIV)
HIV Infections
micro-costing
medicine.disease_cause
Medical and Health Sciences
03 medical and health sciences
0302 clinical medicine
Clinical Research
Virology
Health care
medicine
Immunology and Allergy
Humans
Uganda
HIV antiretroviral therapy
030212 general & internal medicine
Viral suppression
Disease management (health)
Fixed cost
health care economics and organizations
streamlined care
business.industry
Psychology and Cognitive Sciences
1. No poverty
Disease Management
differentiated care
Health Care Costs
Health Services
Biological Sciences
Clinical Science
030112 virology
Antiretroviral therapy
3. Good health
Mental Health
Good Health and Well Being
Infectious Diseases
Family medicine
Costs and Cost Analysis
HIV/AIDS
Business
Infection
Viral load
Zdroj: AIDS (London, England)
AIDS (London, England), vol 32, iss 15
ISSN: 1473-5571
Popis: Author(s): Shade, Starley B; Osmand, Thomas; Luo, Alex; Aine, Ronald; Assurah, Elly; Mwebaza, Betty; Mwai, Daniel; Owaraganise, Asiphas; Mwangwa, Florence; Ayieko, James; Black, Douglas; Brown, Lillian B; Clark, Tamara D; Kwarisiima, Dalsone; Thirumurthy, Harsha; Cohen, Craig R; Bukusi, Elizabeth A; Charlebois, Edwin D; Balzer, Laura; Kamya, Moses R; Petersen, Maya L; Havlir, Diane V; Jain, Vivek | Abstract: OBJECTIVES/DESIGN:As antiretroviral therapy (ART) rapidly expands in sub-Saharan Africa using new efficient care models, data on costs of these approaches are lacking. We examined costs of a streamlined HIV care delivery model within a large HIV test-and-treat study in Uganda and Kenya. METHODS:We calculated observed per-person-per-year (ppy) costs of streamlined care in 17 health facilities in SEARCH Study intervention communities (NCT: 01864603) via micro-costing techniques, time-and-motion studies, staff interviews, and administrative records. Cost categories included salaries, ART, viral load testing, recurring goods/services, and fixed capital/facility costs. We then modeled costs under three increasingly efficient scale-up scenarios: lowest-cost ART, centralized viral load testing, and governmental healthcare worker salaries. We assessed the relationship between community-specific ART delivery costs, retention in care, and viral suppression. RESULTS:Estimated streamlined HIV care delivery costs were $291/ppy. ART ($117/ppy for TDF/3TC/EFV [40%]) and viral load testing ($110/ppy for 2 tests/year [39%]) dominated costs versus salaries ($51/ppy), recurring costs ($5/ppy), and fixed costs ($7/ppy). Optimized ART scale-up with lowest-cost ART ($100/ppy), annual viral load testing ($24/ppy), and governmental healthcare salaries ($27/ppy), lowered streamlined care cost to $163/ppy. We found clinic-to-clinic heterogeneity in retention and viral suppression levels versus streamlined care delivery costs, but no correlation between cost and either retention or viral suppression. CONCLUSIONS:In the SEARCH Study, streamlined HIV care delivery costs were similar to or lower than prior estimates despite including viral load testing; further optimizations could substantially reduce costs further. These data can inform global strategies for financing ART expansion to achieve UNAIDS 90-90-90 targets.
Databáze: OpenAIRE