Imaging in gynecological disease (12): clinical and ultrasound features of invasive and non-invasive malignant serous ovarian tumors

Autor: Manuela Ludovisi, Tina Pasciuto, Dorella Franchi, C. Baima Poma, A.M. Vidal Urbinati, S. Carinelli, Gianfranco Zannoni, A. C. Testa, Francesca Moro, M. C. Moruzzi, Giovanni Scambia
Rok vydání: 2017
Předmět:
Pathology
Serous carcinoma
borderline
grade
papillations
serous
ultrasound
Adenocarcinoma
Mucinous
Adolescent
Adult
Aged
Aged
80 and over
Cystadenocarcinoma
Serous
Female
Humans
Middle Aged
Ovarian Neoplasms
Prognosis
Retrospective Studies
Survival Analysis
Young Adult
Ultrasonography
Doppler
Color
Ovarian tumor
0302 clinical medicine
Nuclear Medicine and Imaging
80 and over
Mucinous
Stage (cooking)
Ultrasonography
030219 obstetrics & reproductive medicine
Radiological and Ultrasound Technology
Ultrasound
Doppler
Obstetrics and Gynecology
General Medicine
Serous fluid
030220 oncology & carcinogenesis
Radiology
medicine.medical_specialty
Reproductive Medicine
Radiology
Nuclear Medicine and Imaging
Cystadenocarcinoma
Color
Adenocarcinoma
03 medical and health sciences
medicine
Radiology
Nuclear Medicine and imaging
Survival analysis
business.industry
Non invasive
Serous
Retrospective cohort study
medicine.disease
Settore MED/40 - GINECOLOGIA E OSTETRICIA
business
Zdroj: Ultrasound in Obstetrics & Gynecology. 50:788-799
ISSN: 0960-7692
DOI: 10.1002/uog.17414
Popis: OBJECTIVES To describe clinical and ultrasound features of different subclasses of malignant serous ovarian tumors according to the World Health Organization 2014 classification. METHODS Patients with a histological diagnosis of borderline tumor (BOT), non-invasive and invasive low-grade serous carcinoma (LGSC) and high-grade serous carcinoma (HGSC), who had undergone preoperative ultrasound examination, were retrospectively identified from two ultrasound centers. The masses were described using the terms of the International Ovarian Tumor Analysis Group. RESULTS Sixty-four (15.8%) women had a serous BOT, 11 (2.7%) a non-invasive LGSC, 31 (7.6%) an invasive LGSC and 300 (73.9%) had a HGSC. The vast majority of BOTs (82.3%) and non-invasive LGSCs (90.9%) were Stage I according to the International Federation of Gynecology and Obstetrics (FIGO) classification scheme, whereas most invasive LGSCs (74.2%) and HGSCs (74.0%) were FIGO Stage III. On ultrasound examination, most borderline lesions were described as unilocular-solid (54.7%) or as multilocular-solid (29.7%) cysts. Papillary projections were present in 52 (81.3%) BOTs. Most non-invasive LGSCs (63.6%) were multilocular-solid cysts and 81.8% had papillary projections. Invasive LGSCs were multilocular-solid cysts in 54.8% of cases, and papillary projections were present in 32.3% of lesions. HGSCs were multilocular-solid (32.7%) or solid (64.0%) masses, with papillary projections in only 7% of cases. CONCLUSIONS Papillary projections were the most typical ultrasound feature of non-invasive (borderline and low-grade) malignant serous tumors, while the presence of solid components but few, if any, papillations was the most representative feature of invasive (low-grade and high-grade) serous tumors. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Databáze: OpenAIRE
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