Computerized or manual? Long term effects of cognitive remediation on schizophrenia
| Autor: | Clare Reeder, Shuping Tan, Yunlong Tan, Fengmei Fan, Yizhuang Zou, Yanli Zhao, Til Wykes, Hongzhen Fan, Dongfeng Zhou, Xiaolin Zhu, Fude Yang, Zhiren Wang |
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| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Trail making business.industry Cognition Neuropsychological Tests medicine.disease Cognitive Remediation Treatment and control groups Psychiatry and Mental health Treatment Outcome Primary outcome Schizophrenia Cognitive remediation therapy Post-hoc analysis medicine Physical therapy Humans Schizophrenic Psychology Single-Blind Method business Biological Psychiatry Follow-Up Studies Diagnosis of schizophrenia |
| Zdroj: | Schizophrenia Research. 239:47-54 |
| ISSN: | 0920-9964 |
| DOI: | 10.1016/j.schres.2021.11.019 |
| Popis: | BACKGROUND Cognitive remediation therapy (CRT) and Computerized CRT (CCRT) improve cognition and functioning, but there is no direct evidence of whether there is an advantage of using a computer. This study fills this gap and extends research evidence to the long-term effect of these two treatments in a large sample of Chinese inpatients with a diagnosis of schizophrenia. METHOD We conducted a randomized single-blind, follow-up study with participants randomized to receive CCRT (n = 144), CRT (n = 72) or Active control (n = 54) for 12 weeks with 4-5 sessions per week. The main outcome was cognition (MATRICS Consensus Cognitive Battery total score, MCCB), and secondary outcomes were cognitive domains, symptoms and functioning assessed at baseline (0 month), post-treatment (3 months) and follow-up (6, 12 and 18 months). RESULTS The primary outcome (MCCB total score) improved in both treatment groups which was maintained at 18 months but did not differ between treatment groups. Post hoc analysis demonstrated that the CRT group had an advantage over CCRT for the Trail Making and Symbol Coding Tests (all p |
| Databáze: | OpenAIRE |
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