Iron(II)/Persulfate Mediated Newman-Kwart Rearrangement
| Autor: | Timothy H. Witney, Hafsa Abdi, Raul Pereira, Thibault Gendron, Erik Årstad |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Aqueous solution
Letter 010405 organic chemistry Organic Chemistry Newman–Kwart rearrangement 010402 general chemistry Persulfate 01 natural sciences Biochemistry 0104 chemical sciences Reaction rate chemistry.chemical_compound chemistry Polymer chemistry Ammonium persulfate Physical and Theoretical Chemistry Acetonitrile |
| Zdroj: | Organic Letters |
| ISSN: | 1523-7052 |
| Popis: | Herein, we report that iron(II)/ammonium persulfate in aqueous acetonitrile mediates the Newman–Kwart rearrangement of O-aryl carbamothioates. Electron-rich substrates react rapidly under moderate heating to afford the rearranged products in excellent yields. The mild conditions, rapid reaction rates, and suitability for scale up offers immediate practical benefits to access functionalized thiophenols. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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