Safe and successful treatment of acne vulgaris with isotretinoin in a patient with chronic granulomatous disease
Autor: | Raúl de Lucas Laguna, Ricardo M. Alonso‐de‐Celada |
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Rok vydání: | 2011 |
Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Recurrent infections Adolescent Mucocutaneous zone Dermatology Naphthalenes Granulomatous Disease Chronic Immune system Chronic granulomatous disease Adapalene hemic and lymphatic diseases Acne Vulgaris medicine Humans skin and connective tissue diseases Isotretinoin Immunodeficiency Acne Benzoyl Peroxide business.industry medicine.disease Treatment Outcome Pediatrics Perinatology and Child Health Dermatologic Agents business medicine.drug |
Zdroj: | Pediatric dermatology. 29(5) |
ISSN: | 1525-1470 |
Popis: | Isotretinoin for acne vulgaris in the setting of chronic granulomatous disease (CGD) is a controversial therapeutic option. In this inherited immunodeficiency, inefficient tissue responses to bacteria and fungi lead to chronic and recurrent infections. Isotretinoin is known to be associated with several mucocutaneous side effects that could worsen the immune response in individuals with CGD. We report the fourth published case of acne vulgaris treated with isotretinoin in an individual with CGD, with a safe and successful outcome. |
Databáze: | OpenAIRE |
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