Imaging features and conspicuity of invasive lobular carcinomas on digital breast tomosynthesis
| Autor: | Romuald Ferré, Caroline Reinhold, Foucauld Chamming's, Atilla Omeroglu, Benoît Mesurolle, Ellen Kao, Ann Aldis |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Digital mammography Breast Neoplasms Surgical specimen 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Medicine Humans Radiology Nuclear Medicine and imaging Neoplasm Invasiveness skin and connective tissue diseases Retrospective Studies Full Paper business.industry Carcinoma Ductal Breast Retrospective cohort study General Medicine Digital Breast Tomosynthesis Institutional review board medicine.disease body regions Carcinoma Lobular Tumour size 030220 oncology & carcinogenesis Invasive lobular carcinoma Female Radiology business Tumour diameter Mammography |
| Zdroj: | The British journal of radiology. 90(1073) |
| ISSN: | 1748-880X |
| Popis: | To review the imaging features of invasive lobular carcinoma (ILC) seen on digital breast tomosynthesis (DBT) in comparison with invasive ductal carcinoma (IDC), and to evaluate whether DBT could improve conspicuity and tumour size assessment of ILC in comparison with digital mammography (DM).Institutional review board with waiver of informed consent was obtained for this retrospective study. Patients with ILC or IDC who underwent DBT and DM at the time of diagnosis were included. DM and DBT images were reviewed in consensus by two breast radiologists in order to assess imaging features, conspicuity and maximum tumour diameter of ILC and IDC. Pathology on the surgical specimen was considered the standard of reference for assessment of tumour size.43 patients (20 patients with ILC and 23 patients with IDC) were included. On DBT, compared with IDC, ILC presented less frequently as masses (40% vs 78%) (p = 0.01) and more frequently as isolated distortion (20% vs 0%) (p = 0.03). ILC presented more often as asymmetries (60%) than masses (20%) on DM (p = 0.02) but not on DBT (35% vs 40%; p = 1.00). Conspicuity of ILC was significantly higher on DBT than on DM (p = 0.002), while the difference between the two techniques was not significant for IDC (p = 0.2). Regarding ILC, concordance in tumour size measurement between DBT and pathology was fair (intraclass correlation coefficient = 0.24).ILC rarely presented as dense masses but frequently demonstrated architectural distortion on DBT. DBT increased lesion conspicuity but failed to accurately assess tumour size of ILC. Advances in knowledge: (1) This study describes specific features of ILC on DBT. (2) It shows that DBT can improve conspicuity of ILC. |
| Databáze: | OpenAIRE |
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