Pressure stability with CPAP devices: A bench evaluation

Autor: Frédéric Lofaso, Véronique Grillier-Lanoir, Karl Leroux, Bruno Louis, Brigitte Fauroux, Maud Boucherie, Daniel Isabey
Přispěvatelé: Institut Mondor de recherche biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), ADEP assistance, Respiratory division, Covidien, Service de pneumologie [CHU Trousseau], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Centre de Recherche Saint-Antoine (UMRS893), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d’Investigation Clinique 1429 [Garches] (CIC 1429), Hôpital Raymond Poincaré [AP-HP]-Institut National de la Santé et de la Recherche Médicale (INSERM), Guellaen, Georges, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Leak
MESH: Continuous Positive Airway Pressure
obstructive sleep apnoea
medicine.medical_treatment
MESH: Equipment Failure Analysis
Pulmonary compliance
MESH: Pulmonary Ventilation
leak effects
Positive-Pressure Respiration
03 medical and health sciences
Work of breathing
MESH: Positive-Pressure Respiration
0302 clinical medicine
Airway resistance
MESH: Computer Simulation
MESH: Airway Resistance
work of breathing
MESH: Humidity
[SDV.BBM] Life Sciences [q-bio]/Biochemistry
Molecular Biology
medicine
Humans
Computer Simulation
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
Continuous positive airway pressure
Lung Compliance
bench test
Pressure drop
MESH: Humans
business.industry
Airway Resistance
Humidity
General Medicine
respiratory tract diseases
Equipment Failure Analysis
Compliance (physiology)
MESH: Work of Breathing
030228 respiratory system
Constant pressure
Anesthesia
Pulmonary Ventilation
business
MESH: Lung Compliance
030217 neurology & neurosurgery
continuous positive airway pressure
Zdroj: Sleep Medicine
Sleep Medicine, Elsevier, 2010, 11 (1), pp.96-9. ⟨10.1016/j.sleep.2009.02.011⟩
Sleep Medicine, 2010, 11 (1), pp.96-9. ⟨10.1016/j.sleep.2009.02.011⟩
ISSN: 1389-9457
DOI: 10.1016/j.sleep.2009.02.011⟩
Popis: International audience; BACKGROUND: Continuous positive airway pressure (CPAP) maintains a constant pressure to reduce the patient's work of breathing (WOB). The aim of this study was to measure the additional WOB imposed by four current CPAP devices during simulation of a difficult but commonly encountered clinical situation. METHOD: Flow contour, respiratory system compliance and total lung-airway resistance of a patient under CPAP were simulated. The devices were tested at a CPAP of 15cm H(2)O with a heated humidifier and a nasal pillow, which increased circuitry resistance and with and without a simulated unintentional leak. RESULTS: With no leak, positive end-expiratory pressure (PEEP) at the interface varied across devices from 14.0 to 15.3cm H(2)O. With a leak of 1L/s, PEEP varied from 11.5 to 17.1cm H(2)O. Imposed inspiratory WOB ranged from less than 0.1J/min to 0.45J/min with no leak, and the range broadened with leaking. Findings were similar for the imposed expiratory WOB. CONCLUSION: The performances of CPAP devices are variable. The device that calibrated for the pressure loss in the circuitry under dynamic conditions and made appropriate pressure adjustments outperformed the other devices.
Databáze: OpenAIRE
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