Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY
Autor: | Taketo Ohmori, Toshihiro Nakamori, Shigeki Furuya, Toshihisa Ohshima, Kayoko Esaki, Motohiro Maebuchi |
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Rok vydání: | 2013 |
Předmět: |
Male
Dipeptide Chemistry Organic Chemistry Deficiency disease Administration Oral Brain General Medicine Dipeptides Pharmacology Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry Increased tyrosine Serine chemistry.chemical_compound Mice Animals Tyrosine Dipeptide SY Phosphoglycerate dehydrogenase Dietary Proteins Molecular Biology Biotechnology |
Zdroj: | Bioscience, biotechnology, and biochemistry. 77(4) |
ISSN: | 1347-6947 |
Popis: | We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration. |
Databáze: | OpenAIRE |
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