Ruthenium Complexes with PYA Pincer Ligands for Catalytic Transfer Hydrogenation of Challenging Substrates
| Autor: | Philipp Melle, Martin Albrecht |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Double bond
Imine Pyridylidene amides chemistry.chemical_element 010402 general chemistry Transfer hydrogenation 01 natural sciences Ligand design chemistry.chemical_compound Amide 540 Chemistry QD1-999 Bond cleavage chemistry.chemical_classification Ligand General Medicine General Chemistry Combinatorial chemistry 0104 chemical sciences Pincer movement Ruthenium Chemistry chemistry 570 Life sciences biology Homogenous catalysis |
| Zdroj: | Melle, Philipp; Albrecht, Martin (2019). Ruthenium Complexes with PYA Pincer Ligands for Catalytic Transfer Hydrogenation of Challenging Substrates. CHIMIA, 73(4), pp. 299-303. Schweizerische Chemische Gesellschaft 10.2533/chimia.2019.299 CHIMIA, Vol 73, Iss 4 (2019) |
| Popis: | Here we highlight the potential of a series of ruthenium complexes with tridentate N,N,N pincer-type ligands featuring two pyridylidene amide (PYA) moieties in the ligand skeleton. They were successfully applied in transfer hydrogenation of ketones and C=C double bonds. Rational ligand design was key for increasing the catalytic performance in the reduction of challenging substrates such as potentially chelating acetylpyridines. The specific reaction profiles indicate catalyst poisoning via imine coordination as well as N,O-bidentate coordination of the substrate or the product. Approaches to mitigate this inhibition are presented. Furthermore, these PYA pincer ruthenium complexes accomplish the selective reduction of the C=C over C=O bond of ?,?-unsaturated ketones such as benzylideneacetone, while other ?,?-unsaturated ketones such as trans-chalcone predominantly underwent oxidative C=C bond cleavage. |
| Databáze: | OpenAIRE |
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