COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine?
| Autor: | Alan R. Hipkiss |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Coronavirus disease 2019 (COVID-19) acetyl-carnosine Carnosine Inflammation Peptide virus Pharmacology Virus Pathology and Forensic Medicine 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine lungs chemistry.chemical_classification Dipeptide aging Cell Biology carnosine 030104 developmental biology chemistry inflammation Serum carnosinase Commentary Nasal administration Neurology (clinical) Geriatrics and Gerontology medicine.symptom 030217 neurology & neurosurgery olfaction |
| Zdroj: | Aging and Disease |
| ISSN: | 2152-5250 |
| Popis: | It is suggested that the non-toxic dipeptide carnosine (beta-alanyl-L-histidine) should be examined as a potential protective agent against COVID-19 infection and inflammatory consequences especially in the elderly. Carnosine is an effective anti-inflammatory agent which can also inhibit CD26 and ACE2 activity. It is also suggested that nasal administration would direct the peptide directly to the lungs and escape the attention of serum carnosinase. |
| Databáze: | OpenAIRE |
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