F-18 FDG Positron Emission Tomography and Benign Fractures
Autor: | Ignac Fogelman, Ivan A. Ho Shon |
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Rok vydání: | 2003 |
Předmět: |
Male
Rib Fractures Bone Neoplasms FDG-Positron Emission Tomography Clinical correlation Sensitivity and Specificity Bone remodeling Diagnosis Differential Fractures Bone Fluorodeoxyglucose F18 medicine Humans False Positive Reactions Radiology Nuclear Medicine and imaging In patient Aged Aged 80 and over medicine.diagnostic_test business.industry Fdg uptake Cancer General Medicine Middle Aged medicine.disease carbohydrates (lipids) Positron emission tomography Spinal Fractures Tomography Radiopharmaceuticals Nuclear medicine business Tomography Emission-Computed |
Zdroj: | Clinical Nuclear Medicine. 28:171-175 |
ISSN: | 0363-9762 |
DOI: | 10.1097/01.rlu.0000053508.98025.01 |
Popis: | Purpose F-18 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) has been used extensively in the imaging of cancer, including metastatic skeletal disease. Although uptake into benign osseous disease has been reported, there is very limited information regarding uptake into benign fractures. This report provides additional information regarding the appearance of benign fractures on FDG-PET images. Materials and methods Four case reports of FDG-PET scanning are presented in patients with proved benign fractures. Results In three of these cases, FDG uptake was noted in fractures when images were obtained 17 days to 8 weeks after injury, with the most avid uptake observed when FDG-PET imaging was performed 17 days after fracture. In the patient in whom imaging was performed 8 weeks after fracture, no uptake of FDG was seen in a benign fracture. Conclusions Fractures may accumulate FDG to varying degrees, and false-positive findings may occur when FDG-PET imaging is performed to assess for metastases, although the different pattern of uptake and clinical correlation usually allows accurate differentiation of fracture from skeletal metastases. |
Databáze: | OpenAIRE |
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