A novel antimicrobial peptide from the sea hare Dolabella auricularia
| Autor: | Jun Kisugi, Masatoshi Yamazaki, Ryosuke Iijima |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
biology Bacteria Immunology Molecular Sequence Data Peptide Dolabella auricularia Antimicrobial biology.organism_classification Mucus Microbiology Anti-Bacterial Agents chemistry Mollusca Dolabellanin A Animals PAGE - Polyacrylamide gel electrophoresis Amino Acid Sequence Amino acid residue Glycoprotein Developmental Biology Glycoproteins |
| Zdroj: | Developmental and comparative immunology. 27(4) |
| ISSN: | 0145-305X |
| Popis: | The sea hare Dolabella auricularia is a marine shell-less gastropod. Four cytotoxic glycoproteins named dolabellanin A, C, E and P were found in the animal previously. An antimicrobial factor was newly isolated from the sea hare's body-wall including skin and mucus. This factor is a novel peptide which consists of 33 amino acid residues, and is called dolabellanin B2. Dolabellanin B2 was cytotoxically effective against some pathogenic microorganisms at a concentration of 2.5–100 μg/ml. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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