Effects of 40Ar and 56Fe ions on retinal photoreceptor cells of the rabbit: implications for manned missions to Mars
| Autor: | J. T. Lett, G. R. Williams |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Atmospheric Science
Time Factors Iron Retinal Photoreceptor Cells Aerospace Engineering Linear energy transfer Retina Ionizing radiation Ion Optics Radiation Ionizing medicine Animals Linear Energy Transfer Photoreceptor Cells New zealand white Argon Physics Analysis of Variance business.industry Astronomy and Astrophysics Dose-Response Relationship Radiation Dose–response relationship Geophysics medicine.anatomical_structure Space and Planetary Science Biophysics General Earth and Planetary Sciences Acute irradiation Rabbits Particle Accelerators business Cosmic Radiation |
| Zdroj: | Advances in space research : the official journal of the Committee on Space Research (COSPAR). 14(10) |
| ISSN: | 0273-1177 |
| Popis: | Losses of photoreceptor cells (rods) from the retinas of New Zealand white (NZW) rabbits were detectable within 2 years after localized acute irradiation of optic and proximal tissues with > or = 7 Gy of 530 MeV u-1 40Ar ions or > or = 2 Gy of 465 MeV u-1 56Fe ions in the Bragg plateau region of energy deposition. Those limits were determined only from an analysis of variance of dose groups because the shapes of the dose response curves at early post-irradiation times are not known, a concern being addressed by experiments in progress. Losses of photoreceptor cells for the period 0.5-2.5 years post-irradiation, determined by provisional linear regression analysis, were approximately 1.7% Gy-1 and 2.5% Gy-1 for 40Ar and 56Fe ions, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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