A new ultrasonic method for measuring minute motion activities on rats
Autor: | M.-T. Lin, Y.C. Li, C.W. Young, Ming-Shing Young |
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Rok vydání: | 1996 |
Předmět: |
Male
Myoclonus Computer science Instrumentation Acoustics Phase (waves) Motor Activity Signal Rats Sprague-Dawley Microcomputers Microcomputer Tremor Animals Waveform Ultrasonics Ultrasonography Behavior Animal Fourier Analysis Electromyography business.industry General Neuroscience Ultrasound Ethology Signal Processing Computer-Assisted Body movement Equipment Design Rats Ultrasonic sensor Telecommunications business Software |
Zdroj: | Journal of Neuroscience Methods. 70:45-49 |
ISSN: | 0165-0270 |
Popis: | A new ultrasonic method is presented for measuring the minute motion activities of rats. A pair of low-cost 40 kHz ultrasonic transducers are used to transmit ultrasound toward a rat and receive the ultrasound reflected from the rat. The relative motion of the rat modulates the phase difference between the transmitted and received ultrasound signals. An 8-bit digital phase meter was designed to record the phase difference signal which was used to reconstruct the relative motion waveform of the rat in an 8751 single-chip microcomputer. The reconstructed data are then sent to a PC-AT microcomputer for further processing. This method employs a spectrum analysis for the reconstructed data and can measure three minute motion activities including locomotor activity (LMA), tremor and myoclonia. Finally, the method has been tested with real animal experiments. The main advantages of this new method are that it is non-invasive, non-contact, low cost and high precision. This new method could also be profitably employed for other behavioral studies and offer potential for research in basic medicine. |
Databáze: | OpenAIRE |
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