Methods and issues in conducting a community-based environmental randomized trial
| Autor: | Arlene Butz, Adrian M. Mosley, Karen Callahan, Gregory B. Diette, Sukon Kanchanaraksa, Jerry A. Krishnan, Timothy J. Buckley, L.J. Swartz, Peyton A. Eggleston, Cynthia S. Rand, Patrick N. Breysse |
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| Rok vydání: | 2004 |
| Předmět: |
Research design
Spirometry medicine.medical_specialty Risk Assessment Biochemistry law.invention Randomized controlled trial law medicine Humans Child Randomized Controlled Trials as Topic General Environmental Science Asthma Maryland medicine.diagnostic_test business.industry Public health Urban Health Environmental Exposure Environmental exposure medicine.disease respiratory tract diseases Clinical trial Research Design Air Pollution Indoor Family medicine Physical therapy Risk assessment business |
| Zdroj: | Environmental Research. 95:156-165 |
| ISSN: | 0013-9351 |
| Popis: | The environment is suspected to play an important role in the prevalence and severity of asthma in inner-city children. This paper describes the implementation and baseline data of an inner-city community-based participatory research clinical trial designed to test the effectiveness of a pollutant and allergen control strategy on children's asthma morbidity. Participants were 100 elementary-school-aged children with asthma, graduates of a school-based asthma education program in East Baltimore. The intervention for half of the randomly assigned families consisted of environmental control education, allergen-proof encasements, pest extermination, and a HEPA air cleaner at the beginning of the study. Controls received the same at the end of the study. Participants visited a clinic for questionnaires, allergy skin testing, spirometry, and blood sample at baseline and 12 months. Home environments, NO(2), O(3), airborne particulates, and allergens were evaluated at baseline and at 6 and 12 months. Asthma morbidity and adherence was assessed quarterly. Collaboration with the community proved very beneficial in creating a study design and procedures acceptable to an inner-city community. |
| Databáze: | OpenAIRE |
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