A COMPARATIVE STUDY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
| Autor: | Amir Rashid, Saleem Ahmed Khan, Robina Anees, Palvasha Waheed, Amena Arif |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
obesity
Medicine (General) medicine.medical_specialty business.industry Insulin medicine.medical_treatment Overweight Control subjects medicine.disease Polycystic ovary Obesity R5-920 Endocrinology Insulin resistance Basal (medicine) insulin resistance Internal medicine medicine Medicine In patient medicine.symptom business |
| Zdroj: | Pakistan Armed Forces Medical Journal, Vol 71, Iss 5, Pp 1746-1751 (2021) |
| ISSN: | 2411-8842 0030-9648 |
| DOI: | 10.51253/pafmj.v71i5.2633 |
| Popis: | Objective: To assess the relationship between obesity and insulin resistance in polycystic ovary syndrome affected women. Study Design: Cross sectional comparative study. Place and Duration of Study: Multidisciplinary Lab-I of Department of Biochemistry, Army Medical College, Rawalpindi, in collaboration with Pakistan Naval Ship Hafeez Hospital, Islamabad from Feb 2018 to Jan 2019. Methodology: One hundred and five selected females (puberty till 25 years of age) were divided into three groups of 35 each. Blood samples were collected an overnight fast (from 8-11 AM). Serum level of insulin was measured and insulin resistance was calculated based on HOMA-IR. Results: HOMA-IR concentrations correlated directly with Basal Metabolic Index, fasting plasma glucose and serum insulin levels. Mean serum insulin level was also elevated in patients with polycystic ovary syndrome (normal weight & overweight) as compared to control subjects (7.4 ± 1.2 mIU/L & 9.1 ± 0.8 mIU/L vs 6.3 ± 1.1 mIU/L; p as 0.003). The insulin resistance was slightly higher in patients with polycystic ovary syndrome as compared to the control subjects (1.4 ± 0.3 & 1.7 ± 0.2 vs. 1.1 ± 0.3; p |
| Databáze: | OpenAIRE |
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