Inhibition of Aldosterone Secretion by Amphenone in Man

Autor:	Jean Crabbé, Don H. Nelson, George W. Thorn, Eric J. Ross, Kendall Emerson, Luis Hernando-Avendano, Albert E. Renold
Rok vydání:	1957
Předmět:	Propiophenones medicine.medical_specialty Aldosterone Adrenal cortex Thyroid Uterus Biological Transport General Medicine Biology Inhibitory postsynaptic potential chemistry.chemical_compound medicine.anatomical_structure Endocrinology chemistry Internal medicine medicine Secretion Thyroid effects
Zdroj:	New England Journal of Medicine. 256:16-21
ISSN:	1533-4406 0028-4793
DOI:	10.1056/nejm195701032560104
Popis:	AMPHENONE was synthesized in 1950 by Allen and Corwin1 and has been shown to possess a high degree of biologic activity in animals2 3 4 and man.5 6 7 In animals the compound has been shown to affect the uterus and the thyroid and the adrenal glands. In man the studies carried out to date have been limited to its effects on the thyroid gland and on the adrenal cortex. The thyroid effects are qualitatively similar to those of thiourea and primarily result in inhibition of the organic binding of iodine.5 , 8 The adrenal effects appear at present to result from an inhibitory action of . . .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a829cb04cfa76f3dd947b34d071f8807 https://doi.org/10.1056/nejm195701032560104 Zobrazit plný text záznamu