Sex Chromosomes and Master Sex-Determining Genes in Turtles and Other Reptiles
| Autor: | Dominique Thépot |
|---|---|
| Přispěvatelé: | Biologie de la Reproduction, Environnement, Epigénétique & Développement (BREED), Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-École nationale vétérinaire d'Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
Male homologous genes Review Biology QH426-470 010603 evolutionary biology 01 natural sciences Genome DNA sequencing RAD-seq Genetic Sex Determination (GSD) Transcriptome 03 medical and health sciences Molecular level Genetics Animals Gene Genetics (clinical) 030304 developmental biology 0303 health sciences Sex Chromosomes RNA [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology Sex Determination Processes snakes Turtles lizards Testis determining factor Evolutionary biology genome coverage squamates Identification (biology) Female |
| Zdroj: | Genes, Vol 12, Iss 1822, p 1822 (2021) Genes Genes, MDPI, 2021, 12 (11), pp.1822. ⟨10.3390/genes12111822⟩ |
| ISSN: | 2073-4425 |
| DOI: | 10.3390/genes12111822⟩ |
| Popis: | International audience; Among tetrapods, the well differentiated heteromorphic sex chromosomes of birds and mammals have been highly investigated and their master sex-determining (MSD) gene, Dmrt1 and SRY, respectively, have been identified. The homomorphic sex chromosomes of reptiles have been the least studied, but the gap with birds and mammals has begun to fill. This review describes our current knowledge of reptilian sex chromosomes at the cytogenetic and molecular level. Most of it arose recently from various studies comparing male to female gene content. This includes restriction site-associated DNA sequencing (RAD-Seq) experiments in several male and female samples, RNA sequencing and identification of Z- or X-linked genes by male/female comparative transcriptome coverage, and male/female transcriptomic or transcriptome/genome substraction approaches allowing the identification of Y- or W-linked transcripts. A few putative master sex-determining (MSD) genes have been proposed, but none has been demonstrated yet. Lastly, future directions in the field of reptilian sex chromosomes and their MSD gene studies are considered. |
| Databáze: | OpenAIRE |
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