Autonomic Dysfunction in Parkinson’s Disease
| Autor: | Ronald F. Pfeiffer |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Parkinson's disease Neurology Gastrointestinal Diseases Urinary system Review Disease Hypotension Orthostatic 03 medical and health sciences Orthostatic vital signs Physical medicine and rehabilitation 0302 clinical medicine Quality of life Advanced disease medicine Effective treatment Animals Humans Disease process Pharmacology (medical) Intensive care medicine Autonomic abnormalities Pharmacology business.industry General Neuroscience Parkinson Disease medicine.disease Sexual Dysfunction Physiological 030104 developmental biology Sexual dysfunction Erectile dysfunction Autonomic Nervous System Diseases Cardiovascular Diseases Physical therapy Neurology (clinical) Neurosurgery medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Neurotherapeutics |
| ISSN: | 1878-7479 1933-7213 |
| DOI: | 10.1007/s13311-020-00897-4 |
| Popis: | Recognition of the importance of nonmotor dysfunction as a component of Parkinson’s disease has exploded over the past three decades. Autonomic dysfunction is a frequent and particularly important nonmotor feature because of the broad clinical spectrum it covers. Cardiovascular, gastrointestinal, urinary, sexual, and thermoregulatory abnormalities all can appear in the setting of Parkinson’s disease. Cardiovascular dysfunction is characterized most prominently by orthostatic hypotension. Gastrointestinal dysfunction can involve virtually all levels of the gastrointestinal tract. Urinary dysfunction can entail either too frequent voiding or difficulty voiding. Sexual dysfunction is frequent and frustrating for both patient and partner. Alterations in sweating and body temperature are not widely recognized but often are present. Autonomic dysfunction can significantly and deleteriously impact quality of life for individuals with Parkinson’s disease. Because effective treatment for many aspects of autonomic dysfunction is available, it is vitally important that assessment of autonomic dysfunction be a regular component of the neurologic history and exam and that appropriate treatment be initiated and maintained. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13311-020-00897-4) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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