Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina
Autor: | Luca Bargelloni, Camillo Martino, Giuseppe Arcangeli, Romina Brunetta, Angela Zampieri, Lisa Grotta, Chiara Papetti, Lisa Carraro, Marco Iannaccone, Giuseppe Martino, Claudio Ciofi, Morgan Smits, Silvia Iori, Tomaso Patarnello, Giulia Dalla Rovere, Nicola Ferri, Barbara Cardazzo, Andrea Ianni, Massimo Milan |
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Přispěvatelé: | Universita degli Studi di Padova, Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Perugia (UNIPG), Facoltà di Bioscienze e tecnologie agro-alimentari e ambientali - Faculty of Bioscience and Agro-Food and Environmental Technology [Teramo], Universita degli studi di Teramo - University of Teramo [Italie] (UNITE), Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI) |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
host‐microbiota interactions
0106 biological sciences 0301 basic medicine crassostrea-gigas ssp damselae Defence mechanisms Disease 01 natural sciences adriatic sea oncorhynchus-mykiss pacific oysters transcriptomics Water Pollutants biology Ecology Microbiota vibrio-splendidus mass mortality Chamelea gallina haliotis-diversicolor-supertexta 010603 evolutionary biology bivalve 03 medical and health sciences pollutant-pathogen interactions Genetics Animals Marine ecosystem bivalve host‐microbiota interactions mass mortality molluscs pollutant–pathogen interactions transcriptomics 14. Life underwater Mortality damselae subsp damselae Ecology Evolution Behavior and Systematics Vibrio molluscs Host Microbial Interactions Host (biology) mass mortalitymolluscs Photobacterium Gene Expression Profiling ACL bivalve host-microbiota interactions mass mortalitymolluscs pollutant–pathogen interactions transcriptomics Outbreak biology.organism_classification Bivalvia rainbow-trout 030104 developmental biology 13. Climate action pollutant–pathogen interactions host-microbiota interactions immune-response [SDE.BE]Environmental Sciences/Biodiversity and Ecology Transcriptome |
Zdroj: | Molecular Ecology Molecular Ecology, Wiley, 2019, 28 (19), pp.4486-4499. ⟨10.1111/mec.15227⟩ |
ISSN: | 0962-1083 1365-294X |
Popis: | WOS:000487521600001; Mass mortalities due to disease outbreaks have recently affected a number of major taxa in marine ecosystems. Climate- and pollution-induced stress may compromise host immune defenses, increasing the risk of opportunistic diseases. Despite growing evidence that mass mortality events affecting marine species worldwide are strongly influenced by the interplay of numerous environmental factors, the reductionist approaches most frequently used to investigate these factors hindered the interpretation of these multifactorial pathologies. In this study, we propose a broader approach based on the combination of RNA-sequencing and 16S microbiota analyses to decipher the factors underlying mass mortality in the striped venus clam, Chamelea gallina, along the Adriatic coast. On one hand, gene expression profiling and functional analyses of microbial communities showed the over-expression of several genes and molecular pathways involved in xenobiotic metabolism, suggesting potential chemical contamination in mortality sites. On the other hand, the down-regulation of several genes involved in immune and stress response, and the over-representation of opportunistic pathogens such as Vibrio and Photobacterium spp. indicates that these microbial species may take advantage of compromised host immune pathways and defense mechanisms that are potentially affected by chemical exposure, resulting in periodic mortality events. We propose the application of our approach to interpret and anticipate the risks inherent in the combined effects of pollutants and microbes on marine animals in today's rapidly changing environment. |
Databáze: | OpenAIRE |
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