Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina

Autor: Luca Bargelloni, Camillo Martino, Giuseppe Arcangeli, Romina Brunetta, Angela Zampieri, Lisa Grotta, Chiara Papetti, Lisa Carraro, Marco Iannaccone, Giuseppe Martino, Claudio Ciofi, Morgan Smits, Silvia Iori, Tomaso Patarnello, Giulia Dalla Rovere, Nicola Ferri, Barbara Cardazzo, Andrea Ianni, Massimo Milan
Přispěvatelé: Universita degli Studi di Padova, Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Perugia (UNIPG), Facoltà di Bioscienze e tecnologie agro-alimentari e ambientali - Faculty of Bioscience and Agro-Food and Environmental Technology [Teramo], Universita degli studi di Teramo - University of Teramo [Italie] (UNITE), Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
host‐microbiota interactions
0106 biological sciences
0301 basic medicine
crassostrea-gigas
ssp damselae
Defence mechanisms
Disease
01 natural sciences
adriatic sea
oncorhynchus-mykiss
pacific oysters
transcriptomics
Water Pollutants
biology
Ecology
Microbiota
vibrio-splendidus
mass mortality
Chamelea gallina
haliotis-diversicolor-supertexta
010603 evolutionary biology
bivalve
03 medical and health sciences
pollutant-pathogen interactions
Genetics
Animals
Marine ecosystem
bivalve
host‐microbiota interactions
mass mortality
molluscs
pollutant–pathogen interactions
transcriptomics
14. Life underwater
Mortality
damselae subsp damselae
Ecology
Evolution
Behavior and Systematics
Vibrio
molluscs
Host Microbial Interactions
Host (biology)
mass mortalitymolluscs
Photobacterium
Gene Expression Profiling
ACL
bivalve
host-microbiota interactions
mass mortalitymolluscs
pollutant–pathogen interactions
transcriptomics
Outbreak
biology.organism_classification
Bivalvia
rainbow-trout
030104 developmental biology
13. Climate action
pollutant–pathogen interactions
host-microbiota interactions
immune-response
[SDE.BE]Environmental Sciences/Biodiversity and Ecology
Transcriptome
Zdroj: Molecular Ecology
Molecular Ecology, Wiley, 2019, 28 (19), pp.4486-4499. ⟨10.1111/mec.15227⟩
ISSN: 0962-1083
1365-294X
Popis: WOS:000487521600001; Mass mortalities due to disease outbreaks have recently affected a number of major taxa in marine ecosystems. Climate- and pollution-induced stress may compromise host immune defenses, increasing the risk of opportunistic diseases. Despite growing evidence that mass mortality events affecting marine species worldwide are strongly influenced by the interplay of numerous environmental factors, the reductionist approaches most frequently used to investigate these factors hindered the interpretation of these multifactorial pathologies. In this study, we propose a broader approach based on the combination of RNA-sequencing and 16S microbiota analyses to decipher the factors underlying mass mortality in the striped venus clam, Chamelea gallina, along the Adriatic coast. On one hand, gene expression profiling and functional analyses of microbial communities showed the over-expression of several genes and molecular pathways involved in xenobiotic metabolism, suggesting potential chemical contamination in mortality sites. On the other hand, the down-regulation of several genes involved in immune and stress response, and the over-representation of opportunistic pathogens such as Vibrio and Photobacterium spp. indicates that these microbial species may take advantage of compromised host immune pathways and defense mechanisms that are potentially affected by chemical exposure, resulting in periodic mortality events. We propose the application of our approach to interpret and anticipate the risks inherent in the combined effects of pollutants and microbes on marine animals in today's rapidly changing environment.
Databáze: OpenAIRE
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